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The Missouri Department of Natural Resources describes a Biomedical Manufacturing business as:

Biomedical Manufacturing is the production of medical grade implant devices used internally in the human body such as pacemakers, bone prosthetics or metal plates.

You may need some or all of the following permits for a Biomedical Manufacturing business:

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Hazardous Waste/ Infectious Waste Transporter License

If you or your business plans to transport used oil, hazardous waste (combustible liquids, corrosives, poisons/ toxins, flammable liquids, flammable solids, PCB's) or infectious waste in Missouri, you are required to obtain a Hazardous Waste Transporter License.

Even though the request is approved by both Missouri Department of Transportation (MoDOT) and the Missouri Department of Natural Resources, you must apply for and renew the license through MoDOT. For more information, please visit MoDOT's Hazardous Waste Transport webpage.
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Major Water User Registration

If you or your business is capable of producing 100,000 gallons per day, or approximately 70 gallons per minute, including all wells or surface intakes, you are required to register with the department as a Major Water User. This registration is not for permitting purposes or to regulate water usage. Major water users are required by law to report the volume of water they used by March 31 of the year following the usage. Registration is required in order to submit reports.

The Major Water Users Program is established to simply gather water use data. Missouri collects water use data to better understand and manage the state’s water inventory. For more information, or to complete the online registration, please visit the Major Water Users webpage.